About ac-5

Summary of the data.

The data contain in vivo whole-cell recordings from primary auditory cortex (A1) of anesthetized wild-type mice (C57BL/6, female, 4–11 weeks of age) by the mixture of ketamine and xylazine. Current-clamp recordings were obtained by applying two stimuli, pure tones (n = 66 neurons; ~2 min for one set of tones) and complex sounds (dynamic moving ripples, DMRs; n = 40 neurons; ~10 min for each recording). Thus, 40 neurons have paired recordings for the response comparison between pure tones and DMR stimuli. Voltage-clamp recordings (n = 31 neurons) were collected for excitatory currents (n = 27 neurons; holding at approximately -80mV; ~10 min for each recording) and for inhibitory currents (n = 12 neurons; holding at approximately 0 mV; ~10min for each recording) by applying the DMR stimulus. Thus, 8 neurons have paired recordings of excitation and inhibition. Results from the experiments are described in:

Kyunghee X. Kim, Craig A. Atencio, Christoph E. Schreiner. Stimulus dependent transformations between synaptic and spiking receptive fields in auditory cortex. Nature Communications 11, 1102 (2020) https://doi.org/10.1038/s41467-020-14835-7

Format of the Data

The data files are organized in matlab, wav and spr format. Details are in the document linked to at the bottom of this page. Total size of the data is about 7.3 GB.

Conditions for using the data

If you publish any work using the data, please cite the publication above (Kim et al., 2020), and also cite the data set using the following:

Kyunghee X. Kim, Craig A. Atencio, Christoph E. Schreiner (2020); In vivo whole-cell recordings to complex sounds in the mouse auditory cortex. CRCNS.org
http://dx.doi.org/10.6080/K07H1GSS

The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set.  The DOI was created using DataCite (www.datacite.org) and the California Digital Library, "EZID" system (n2t.net/ezid/).

How to download the data

The data can be downloaded from:

https://portal.nersc.gov/project/crcns/download/ac-5

A CRCNS.org account is required.  This link allows bulk downloading of multiple files using the download script as described in the "Alternative download method" section on the download page.

Getting help using the data

If you have questions about using the data, post them on the forum for using data sets. 

Documentation file