AC-2
?
Best
Cesare
Hi Cesare,
Thanks for your interest in these data. As described in the Methods section of DeWeese & Zador, J Neurophy 2004, I included QX-314, an intracellular sodium channel blocker, in the internal solution of my patch electrode for all recordings that didn't involve TTX application to the surface of the cortex (TTX, or tetrodotoxin, is an extracellular sodium channel blocker). So one way or the other, I was pharmacologically preventing spiking in these neurons, though you might find a few spikes across the data set. I hope this is helpful!
Mike
Hi Mike,
do you also have data including whole spikes? If yes would you be willing to share them in the database?
Thanks a lot for sharing your beautiful data.
Best Regards,
Cesare
Previously Mike DeWeese wrote:
Hi Cesare,
Thanks for your interest in these data. As described in the Methods section of DeWeese & Zador, J Neurophy 2004, I included QX-314, an intracellular sodium channel blocker, in the internal solution of my patch electrode for all recordings that didn't involve TTX application to the surface of the cortex (TTX, or tetrodotoxin, is an extracellular sodium channel blocker). So one way or the other, I was pharmacologically preventing spiking in these neurons, though you might find a few spikes across the data set. I hope this is helpful!
Mike