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You are here: Home Data Sets Motor cortex alm-3 (anterior lateral motor cortex 3) About alm-3

About alm-3

Description of dataset alm-3 (anterior lateral motor cortex 3).

Summary of the data

These experiments measure neuronal responses after transiently silencing parts of mouse premotor cortex (anterior lateral motor cortex, ALM). The data represent extracellular recordings from ALM neurons of adult mice performing pole location discrimination. Data from 91 recording sessions are included in this release. This dataset contains data from 19 mice (age > P60). 5 VGAT-ChR2-EYFP mice (Jackson laboratory, JAX Stock#014548) and 7 PV-ires-cre crossed to Rosa26-LSL-ReaChR, red-shifted channelrhodopsin reporter mice (JAX 24846), were used for simultaneous electrophysiology and photoinhibition. 7 mice (6 VGAT-ChR2-EYFP, 1 PV × ReaChR mice) were used for the callosotomy experiment. The experiments (including experiment methods) are described in the following publication:

Li N, Daie K, Svoboda K, Druckmann S (2016). Robust neuronal dynamics in premotor cortex during motor planning. Nature. 7600:459-64. doi: 10.1038/nature17643 

A paper describing similar experiments is:

Flow of cortical activity underlying a tactile decision in mice. Guo ZV, Li N, Huber D, Ophir E, Gutnisky D, Ting JT, Feng G, Svoboda K.” Neuron. 2014 Jan 8;81(1):179-94. doi: 10.1016/j.neuron.2013.10.020.

Format of the data

The data are stored in three types of Matlab files: one file contains the metadata describing the experiment; another contains the processed data; and the third contains raw voltage traces.  Total size of the data without the raw voltage traces is about 12GB (compressed).  Total size of the raw voltage traces is about (533 GB).  Matlab scripts are included which make demo plots of data and also reproduce some of the figures in the Li, et al., 2016 paper.  Details are given in file crcns_alm-3_data_description.pdf.

Conditions for usage of this data in publications

If you publish any work using the data, please cite the Nuo Li, et. al., publication above and also cite the data set in the following recommended format:

Li, Daie, Svoboda, Druckman (2016); Data and simulations related to: Robust neuronal dynamics in premotor cortex during motor planning. Li, Daie, Svoboda, Druckman, Nature.

The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set.  The DOI was created using DataCite ( and the California Digital Library, "EZID" system (

How to download the data

Data may be downloaded from:
A account is required. See the download link for more instructions.

Getting help using the data

If you have questions about using the data, please post them on the forum for using data sets.

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