About pfc-7

Information about pfc-7 (prefrontal cortex, number 7).

Summary.

This dataset contains single unit recordings made from several different subregions of prefrontal cortex in 2 macaque monkeys (dorsolateral prefrontal cortex; orbitofrontal cortex; anterior cingulate cortex) performing an information search and decision-making task. Some of the neurons are simultaneously recorded across the different areas (during a typical recording session 8-24 electrodes were lowered simultaneously, see supplementary Table S1 in Hunt/Malalasekera et al., 2018). In the paper, we stack condition-averaged responses across the population to create pseudopopuluations, which reveal the distinct contributions of each PFC subregion to information search and reward-guided choice. Results from the experiments are described in:

Triple dissociation of attention and decision computations across prefrontal cortex. Laurence T. Hunt, W.M. Nishantha Malalasekera, Archy O. de Berker, Simon F. Farmer, Timothy E. J. Behrens and Steven W. Kennerley. Nature Neuroscience in press (2018) doi: to be confirmed

The dataset includes MATLAB scripts that should straightforwardly reproduce all of the figures in the paper. It also includes raw spike times and LFP data for further analysis, and metadata associated with the experiment.

Format of the data.

Data are stored in Matlab files. Total size of the data is about 59 GB. Details about the data are in the documents linked to at the bottom of this page.

How to download the data.

The data must be downloaded from:

https://portal.nersc.gov/project/crcns/download/pfc-7

A CRCNS.org account is required. This link allows bulk downloading of multiple files using the download script as described in the "Alternative download method" section on the download page.

Getting help using the data.

If you have questions about using the data, post them on the forum for using data sets.

Conditions for using the data

These data required years of effort to collect. It is our lab policy that any preprint or peer-reviewed publication using these data should normally list as authors the people who collected the data (Laurence Hunt and Nishantha Malalasekera), and the group leader under whose responsibility the data has been collected (Steve Kennerley). Please contact the principal investigator ([email protected]) and the lead author ([email protected]) to discuss any publications that may arise from this dataset. In addition, please cite the publication given above (Hunt/Malalasekera et al., 2018) and also cite the data set using the following:

Hunt L.T., Malalasekera W.M.N, Kennerley, S.W. (2018); Recordings from three subregions of macaque prefrontal cortex during an information search and choice task. CRCNS.org
http://dx.doi.org/10.6080/K0PZ5712

The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set. The DOI was created using DataCite (www.datacite.org) and the California Digital Library, "EZID" system (n2t.net/ezid/).