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About hc-25

Information about the hc-25 data set.


Action potentials and local field potentials (LFPs) were simultaneously recorded from the dorsal hippocampus (CA1) and medial prefrontal cortex (mPFC) of nine Long-Evans rats during sleep and behavior. During behavior, the rats explored a rectangular enclosure with two identical objects (spatial object recognition task). Sleep sessions include unperturbed sleep, timed stimulation of motor cortex triggered by hippocampal ripples, and delayed (control) stimulation. Results from the experiments are described in:

N. Maingret, G. Girardeau, R. Todorova, M. Goutierre, M. Zugaro (2016). Hippocampo-cortical coupling mediates memory consolidation during sleep. Nature Neuroscience 19(7):959-64

R. Todorova and M. Zugaro (2019). Isolated cortical computations during delta waves supports memory consolidation. Science (in press).

The data set includes 35 sessions, each consisting of pre-task sleep, task, and post-task sleep. Hippocampal and cortical signals were recorded using sixteen independently movable tetrodes (64 channels). Data include sorted spikes (times, clusters, featres, and full waveforms), LFPs (at 1250 Hz), positions (coordinates of head-mounted LEDs), and experiment descriptions. They are provided in the standard, open format of NeuroSuite (L. Hazan,, see Hazan et al., 2006). Data analyses described in the above articles used our free (GPL-licensed) Freely Moving Animal Toolbox (FMAToolbox, M. Zugaro, and custom scripts provided in the archive.

Format of the data

The open data format is described in Hazan et al. (2006) and on our NeuroSuite website (L. Hazan, Data can be readily loaded in Matlab using our free (GPL-licensed) Freely Moving Animal Toolbox (FMAToolbox, M. Zugaro,, which also includes extensive documentation. More information about the data is given in the document linked to at the bottom of this page. Total data size is about 900 GB.

Conditions for usage of this data in publications

Please contact Michaël Zugaro if you are planning to use these data for a publication in order to discuss potential authorship. In any case, if you publish any work using the data, please cite the publications above and the data set as follows, using the following:

N. Maingret, Todorova R. and M. Zugaro (2019). Recordings and timed stimulation of rat dorsal hippocampal area CA1 and medial prefrontal cortex during behavior and sleep.

The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set.  The DOI was created using DataCite ( and the California Digital Library, "EZID" system (

How to download the data

Data may be downloaded from:
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Getting help using the data

If you have questions about using the data, please post them on the forum for using data sets.

Documentation file

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