About hc-30

Summary

This data set contains functional calcium imaging recordings from mice CA1 hippocampal region. We tracked the concurrent calcium dynamics of hundreds of CA1 pyramidal neurons in 12 mice (151-497 neurons per session, median 235; a total of 27,898 neurons over 110 sessions) that ran back and forth on a 120-cm-long linear track to collect a water reward. The behavioral sessions lasted around 20 min where animals performed between 150 to 380 runs on the track per session. Animals could not obtain rewards twice on the same side of the track, so they were forced to alternate by the behavioral box computer control. Using our event detection algorithm, we quantified CA1 neurons’ calcium activity responses from the raw calcium trace. We convolved each event trace with the function (t)=(t/)(1-t/), where =0.2s sampled at 20Hz from t = 0.05 to 1.5s. This convolution simulates a spike burst from each calcium event.  The data was used in the following publication:

Noise correlations in neural ensemble activity limit the accuracy of hippocampal spatial representations. Omer Hazon, Victor H. Minces, David P. Tomàs, Surya Ganguli, Mark J. Schnitzer, Pablo E. Jercog, (2022)

Format of the data

The data is stored in a matlab file. Details of the format are given in the document linked to at the bottom of this page. Total data size is about 136 MB.

Conditions for usage of this data in publications

For use of data in publication please consult Pablo Jercog and Mark Schnitzer prior to publication. Also, if you publish any work using the data, please cite the publication above (Hazon. O. et al., 2022) also cite the data set using the following:

Pablo Jercog and Mark Schnitzer (2022); Functional calcium imaging recordings of hippocampal area CA1 from mice performing a linear track task. CRCNS.org.
http://dx.doi.org/10.6080/K0GH9G5X

The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set.  The DOI was created using DataCite (www.datacite.org) and the California Digital Library, "EZID" system (ezid.cdlib.org).

How to download the data

Data may be downloaded from:
https://portal.nersc.gov/project/crcns/download/hc-30
A CRCNS.org account is required.

Getting help using the data

If you have questions about using the data, please post them on the forum for using data sets.

Documentation files