About hc-7
Summary
The data set contains raw data and values of inhibitory transmission parameters (IPSC rise, decay, amplitude and short-term plasticity) between interneurons and their interneuron/pyramidal cell targets in response to for different physiologically relevant firing patterns. We measured the parameters of transmission from pairs of CA3 area PV positive basket and axo-axonic, as well as CCK positive basket and dendrite targeting neurons in mouse in vitro hippocampal slices (postnatal 19-25 days).
The data were used to produce results described in the following paper:
Zsolt Kohus, Szabolcs Káli, Laura Rovira-Esteban, Dániel Schlingloff, Orsolya Papp, Tamás F Freund, Norbert Hájos, Attila I Gulyás.
Properties and dynamics of inhibitory synaptic communication within the CA3 microcircuits of pyramidal cells and interneurons expressing PV or CCK.
J Physiol. 2016 Apr 1. doi: 10.1113/JP272231.
https://www.ncbi.nlm.nih.gov/pubmed/27038232
Format of the data
The data is stored in both TAB separated ASCII files and binary files which contain 4 byte floating point values. Total size of the data is about 224 MB (compressed). Details of the data and format are given in the data description document, linked to at the bottom of this page.
How to download the data
Data may be downloaded from:
https://portal.nersc.gov/project/crcns/download/hc-7
A CRCNS.org account is required. See the download link for more instructions.
Getting help using the data.
If you have questions about using the data, post them on the forum for using data sets.
How to cite the data
Publications created through usage of the data should cite the publication given above and also cite the data set in the following recommended format:
Zsolt Kohus, Attila I Gulyás. (2016) Temporal properties of mouse hippocampal CA3 area PV and CCK inhibitory neuron transmission measured by physiologically relevant action potential sequences. CRCNS.org.
http://dx.doi.org/10.6080/K0MK69T5
The above citation uses a Digital Object Identifier (DOI) which is assigned to the data set. The DOI was created using DataCite (www.datacite.org) and the California Digital Library, "EZID" system (n2t.net/ezid/).
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